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Target
Proteinase-activated receptor 2
Ligand
BDBM50609292
Substrate
n/a
Meas. Tech.
ChEMBL_2277301
IC50
0.700000±n/a nM
Citation
 Garrido, A; Vera, G; Delaye, PO; Enguehard-Gueiffier, C Imidazo[1,2-b]pyridazine as privileged scaffold in medicinal chemistry: An extensive review. Eur J Med Chem 226:0 (2021) [PubMed] 
Target
Name:
Proteinase-activated receptor 2
Synonyms:
F2RL1 | GPR11 | PAR2 | PAR2_HUMAN
Type:
PROTEIN
Mol. Mass.:
44152.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1497756
Residue:
397
Sequence:
MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
  
Inhibitor
Name:
BDBM50609292
Synonyms:
CHEMBL5273903
Type:
Small organic molecule
Emp. Form.:
C28H36FN5O3
Mol. Mass.:
509.6155
SMILES:
CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN([C@@H](C)C1)C(=O)[C@H](O)CC(C)(C)C)-c1ccc(F)cc1 |r|
Structure:
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