Reaction Details Report a problem with these data
Target
Sulfotransferase 2A1
Ligand
BDBM23420
Substrate
n/a
Meas. Tech.
ChEMBL_2281003
IC50
34000±n/a nM
Citation
 Tanwar, AK; Dhiman, N; Kumar, A; Jaitak, V Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. Eur J Med Chem 213:0 (2021) [PubMed] 
Target
Name:
Sulfotransferase 2A1
Synonyms:
2.8.2.14 | 2.8.2.2 | Bile salt sulfotransferase | Hydroxysteroid sulfotransferase | ST-20 | ST2A1 | St2a1 | Sulfotransferase 2A1 | Sult2a1
Type:
PROTEIN
Mol. Mass.:
33139.75
Organism:
Rattus norvegicus
Description:
ChEMBL_17057
Residue:
284
Sequence:
MPDYTWFEGIPFHAFGISKETLQNVCNKFVVKDEDLILLAYPKSGTNWLIEIVCLIQTKGDPKWIQSVTIWDRSPWIETDLGYDMLIKKKGPRLITSHLPMHLFSKSLFSSKAKVIYLVRNPRDVLVSGYYFWGNSTLAKKPDSLGTYVEWFLKGNVLYGSWFEHIRAWLSMREWDNFLLLYYEDMKKDTMGTIKKICDFLGKKLEPDELDLVLKYSSFQVMKENDMSNYSLLMKKSIFTGIGLMRKGTVGDWKNHFTVSQAEAFDKVFQEKMAGFPPGMFPWE
  
Inhibitor
Name:
BDBM23420
Synonyms:
7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one | CHEMBL8145 | Daidzein | US8552057, 7
Type:
isoflavone
Emp. Form.:
C15H10O4
Mol. Mass.:
254.2375
SMILES:
Oc1ccc(cc1)-c1coc2cc(O)ccc2c1=O
Structure:
Search PDB for entries with ligand similarity: