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Target
Tyrosinase
Ligand
BDBM50559076
Substrate
n/a
Meas. Tech.
ChEMBL_2282157
IC50
1.1±n/a nM
Citation
 Li, J; Feng, L; Liu, L; Wang, F; Ouyang, L; Zhang, L; Hu, X; Wang, G Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem 224:0 (2021) [PubMed] 
Target
Name:
Tyrosinase
Synonyms:
LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB
Type:
Protein
Mol. Mass.:
60388.08
Organism:
Human
Description:
P14679
Residue:
529
Sequence:
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
  
Inhibitor
Name:
BDBM50559076
Synonyms:
CHEMBL4743159
Type:
Small organic molecule
Emp. Form.:
C13H14N2O3S
Mol. Mass.:
278.327
SMILES:
CC(C)C(=O)Nc1nc(cs1)-c1ccc(O)cc1O
Structure:
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