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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50292302
Substrate
n/a
Meas. Tech.
ChEMBL_440929 (CHEMBL890019)
Ki
950±n/a nM
Citation
 Hauck, SI; Cederberg, C; Doucette, A; Grosser, L; Hales, NJ; Poon, G; Gravestock, MB New carbon-linked azole oxazolidinones with improved potency and pharmacokinetics. Bioorg Med Chem Lett 17:337-40 (2007) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Human
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM50292302
Synonyms:
CHEMBL390465 | N-(((S)-3-(3-fluoro-4-(3-methylisoxazol-5-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
Type:
Small organic molecule
Emp. Form.:
C16H16FN3O4
Mol. Mass.:
333.3143
SMILES:
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(-c2cc(C)no2)c(F)c1
Structure:
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