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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50029810
Substrate
n/a
Meas. Tech.
ChEMBL_2284159
IC50
2.0±n/a nM
Citation
 Tripathi, AC; Upadhyay, S; Paliwal, S; Saraf, SK Privileged scaffolds as MAO inhibitors: Retrospect and prospects. Eur J Med Chem 145:445-497 (2018) [PubMed] 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50029810
Synonyms:
2-[5-(4-Benzyloxy-phenyl)-tetrazol-2-yl]-ethanol | CHEMBL145760
Type:
Small organic molecule
Emp. Form.:
C16H16N4O2
Mol. Mass.:
296.3238
SMILES:
OCCn1nnc(n1)-c1ccc(OCc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: