Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM38549
Substrate
n/a
Meas. Tech.
ChEMBL_2298862
Ki
10±n/a nM
Citation
 Wei, L; Xiang, K; Kang, H; Yu, Y; Fan, H; Zhou, H; Hou, T; Ge, Y; Wang, J; Guo, Z; Chen, Y; Zhao, Y; Liang, X Development and Characterization of Fluorescent Probes for the G Protein-Coupled Receptor 35. ACS Med Chem Lett 14:411-416 (2023) [PubMed] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM38549
Synonyms:
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazino]ethoxy]ethanol | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]ethanol | 4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid | 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-2-naphthoic acid | CHEMBL170358 | CHEMBL177880 | HYDROXYZINE PAMOATE | MLS000028605 | Pamoic acid | SMR000058728 | US11744839, Compound of formula 8 | cid_25096
Type:
Small organic molecule
Emp. Form.:
C23H16O6
Mol. Mass.:
388.3695
SMILES:
OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
Structure:
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