Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50208418
Substrate
n/a
Meas. Tech.
ChEMBL_443247 (CHEMBL893497)
IC50
16400±n/a nM
Citation
 Tiwari, AK; Mishra, AK; Bajpai, A; Mishra, P; Singh, S; Sinha, D; Singh, VK Synthesis and evaluation of novel benzimidazole derivative [Bz-Im] and its radio/biological studies. Bioorg Med Chem Lett 17:2749-55 (2007) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50208418
Synonyms:
2-[5-((E)-2-biphenyl-4-yl-vinyl)-2-hydroxy-benzo[4,5]imidazo[1,2-a]quinolin-1-ylmethyl]-isoindole-1,3-dione | CHEMBL233457 | VL-0494
Type:
Small organic molecule
Emp. Form.:
C38H25N3O3
Mol. Mass.:
571.6234
SMILES:
Oc1ccc2c(\C=C\c3ccc(cc3)-c3ccccc3)cc3nc4ccccc4n3c2c1CN1C(=O)c2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: