Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50208420
Substrate
n/a
Meas. Tech.
ChEMBL_443246 (CHEMBL893496)
IC50
942±n/a nM
Citation
 Tiwari, AK; Mishra, AK; Bajpai, A; Mishra, P; Singh, S; Sinha, D; Singh, VK Synthesis and evaluation of novel benzimidazole derivative [Bz-Im] and its radio/biological studies. Bioorg Med Chem Lett 17:2749-55 (2007) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50208420
Synonyms:
2-[2-hydroxy-5-((E)-styryl)-benzo[4,5]imidazo[1,2-a]quinolin-1-ylmethyl]-isoindole-1,3-dione | CHEMBL233647
Type:
Small organic molecule
Emp. Form.:
C32H21N3O3
Mol. Mass.:
495.5274
SMILES:
Oc1ccc2c(\C=C\c3ccccc3)cc3nc4ccccc4n3c2c1CN1C(=O)c2ccccc2C1=O
Structure:
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