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Target
D(1A) dopamine receptor
Ligand
BDBM50252322
Substrate
n/a
Meas. Tech.
ChEMBL_491772 (CHEMBL937843)
Ki
2520±n/a nM
Citation
 Liu, Z; Chen, X; Yu, L; Zhen, X; Zhang, A Synthesis and pharmacological investigation of novel 2-aminothiazole-privileged aporphines. Bioorg Med Chem 16:6675-81 (2008) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50252322
Synonyms:
CHEMBL520610 | R-(-)-2,3:[4,5-b]-2'-Aminothiazolo-10,11-dihydroxyaporphine
Type:
Small organic molecule
Emp. Form.:
C18H17N3O2S
Mol. Mass.:
339.411
SMILES:
CN1CCc2c3[C@H]1Cc1ccc(O)c(O)c1-c3cc1nc(N)sc21 |r|
Structure:
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