Reaction Details Report a problem with these data
Target
Group IIE secretory phospholipase A2
Ligand
BDBM50053137
Substrate
n/a
Meas. Tech.
ChEMBL_489275 (CHEMBL990831)
IC50
35±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group IIE secretory phospholipase A2
Synonyms:
PA2GE_MOUSE | Pla2g2e
Type:
PROTEIN
Mol. Mass.:
15949.46
Organism:
Mus musculus
Description:
ChEMBL_489275
Residue:
142
Sequence:
MKPPIALACLCLLVPLAGGNLVQFGVMIERMTGKPALQYNDYGCYCGVGGSHWPVDETDWCCHAHDCCYGRLEKLGCDPKLEKYLFSITRDNIFCAGRTACQRHTCECDKRAALCFRHNLNTYNRKYAHYPNKLCTGPTPPC
  
Inhibitor
Name:
BDBM50053137
Synonyms:
(1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indolizin-8-yloxy)-acetic acid | CHEMBL332993
Type:
Small organic molecule
Emp. Form.:
C27H24N2O5
Mol. Mass.:
456.4899
SMILES:
CCc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O
Structure:
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