Reaction Details Report a problem with these data
Target
Group IIE secretory phospholipase A2
Ligand
BDBM50262842
Substrate
n/a
Meas. Tech.
ChEMBL_489275 (CHEMBL990831)
IC50
12±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group IIE secretory phospholipase A2
Synonyms:
PA2GE_MOUSE | Pla2g2e
Type:
PROTEIN
Mol. Mass.:
15949.46
Organism:
Mouse
Description:
ChEMBL_489275
Residue:
142
Sequence:
MKPPIALACLCLLVPLAGGNLVQFGVMIERMTGKPALQYNDYGCYCGVGGSHWPVDETDWCCHAHDCCYGRLEKLGCDPKLEKYLFSITRDNIFCAGRTACQRHTCECDKRAALCFRHNLNTYNRKYAHYPNKLCTGPTPPC
  
Inhibitor
Name:
BDBM50262842
Synonyms:
Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetamide | CHEMBL514692
Type:
Small organic molecule
Emp. Form.:
C27H25N3O6S
Mol. Mass.:
519.569
SMILES:
CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cccc2n1Cc1ccccc1
Structure:
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