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Target
Mu-type opioid receptor
Ligand
BDBM50272229
Substrate
n/a
Meas. Tech.
ChEMBL_510434 (CHEMBL1003110)
IC50
1.21±n/a nM
Citation
 Balboni, G; Fiorini, S; Baldisserotto, A; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. J Med Chem 51:5109-17 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
Mu-opioid receptor
Type:
PROTEIN
Mol. Mass.:
44729.40
Organism:
Cavia porcellus
Description:
ChEMBL_510437
Residue:
400
Sequence:
MDSGAVPGNASDCTDPFAQSTCSPAPSPGSWTNLSHLDGNLSDPCGPNRTDLVGSDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50272229
Synonyms:
CHEMBL444197 | H-Dmt-Tic-NH-(R)CH(CH2-COOH)-Bid
Type:
Small organic molecule
Emp. Form.:
C31H33N5O5
Mol. Mass.:
555.6242
SMILES:
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](CC(O)=O)c1nc2ccccc2[nH]1 |r|
Structure:
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