Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50272081
Substrate
n/a
Meas. Tech.
ChEMBL_510435 (CHEMBL1003111)
IC50
2.57±n/a nM
Citation
 Balboni, G; Fiorini, S; Baldisserotto, A; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. J Med Chem 51:5109-17 (2008) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50272081
Synonyms:
2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid phenylcarbamoylmethyl-amide | CHEMBL501451 | H-Dmt-Tic-Gly-NH-Ph
Type:
Small organic molecule
Emp. Form.:
C29H32N4O4
Mol. Mass.:
500.5888
SMILES:
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)Nc1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: