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Target
Disks large homolog 4
Ligand
BDBM50252713
Substrate
n/a
Meas. Tech.
ChEMBL_539186 (CHEMBL1024690)
Ki
2300±n/a nM
Citation
 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Røder, MU; Pang, GF; Clausen, RP; Jemth, P; Strømgaard, K Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem 51:6450-9 (2008) [PubMed]  Article 
Target
Name:
Disks large homolog 4
Synonyms:
DLG4 | DLG4_HUMAN | PSD95
Type:
PROTEIN
Mol. Mass.:
80483.80
Organism:
Homo sapiens (Human)
Description:
ChEMBL_736705
Residue:
724
Sequence:
MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL
  
Inhibitor
Name:
BDBM50252713
Synonyms:
CHEMBL492642 | FETAV
Type:
Small organic molecule
Emp. Form.:
C26H39N5O9
Mol. Mass.:
565.616
SMILES:
CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(C)O)C(O)=O |r|
Structure:
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