Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50276039
Substrate
n/a
Meas. Tech.
ChEMBL_496860 (CHEMBL998529)
Ki
103000±n/a nM
Citation
 Ghosh, KS; Debnath, J; Pathak, T; Dasgupta, S Using proton nuclear magnetic resonance to study the mode of ribonuclease A inhibition by competitive and noncompetitive inhibitors. Bioorg Med Chem Lett 18:5503-6 (2008) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
RIB1 | RNAS1_HUMAN | RNASE1 | RNAse A | RNS1 | Ribonuclease A | Ribonuclease pancreatic
Type:
Protein
Mol. Mass.:
17653.66
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
156
Sequence:
MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
  
Inhibitor
Name:
BDBM50276039
Synonyms:
1-[3-(4-CARBOXYPIPERIDIN-1-YL)-3-DEOXY-BETA-D-ARABINOFURANOSYL]PYRIMIDINE-2,4(1H,3H)-DIONE | 3'-[1-(4-carboxylpiperdinyl)]-3'-deoxy-ara-uridine | CHEMBL469949
Type:
Small organic molecule
Emp. Form.:
C15H21N3O7
Mol. Mass.:
355.3431
SMILES:
OC[C@H]1O[C@H]([C@@H](O)[C@@H]1N1CCC(CC1)C(O)=O)n1ccc(=O)[nH]c1=O |r|
Structure:
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