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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50259621
Substrate
n/a
Meas. Tech.
ChEMBL_500941 (CHEMBL972369)
Ki
600±n/a nM
Citation
 Van der Walt, EM; Milczek, EM; Malan, SF; Edmondson, DE; Castagnoli, N; Bergh, JJ; Petzer, JP Inhibition of monoamine oxidase by (E)-styrylisatin analogues. Bioorg Med Chem Lett 19:2509-13 (2009) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50259621
Synonyms:
(E)-5-(3-Fluorostyryl)isatin | CHEMBL506301
Type:
Small organic molecule
Emp. Form.:
C16H10FNO2
Mol. Mass.:
267.2545
SMILES:
Fc1cccc(\C=C\c2ccc3NC(=O)C(=O)c3c2)c1
Structure:
Search PDB for entries with ligand similarity: