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Target
D(1A) dopamine receptor
Ligand
BDBM50007572
Substrate
n/a
Meas. Tech.
ChEBML_58184
IC50
>15000±n/a nM
Citation
 Jaen, JC; Caprathe, BW; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG Synthesis and dopaminergic activity of the enantiomers of 6-methyl-4,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine (PD 128483). Bioorg Med Chem Lett 1:539-544 (1991)    Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50007572
Synonyms:
2-Amino-6-propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-6-ium
Type:
Small organic molecule
Emp. Form.:
C13H20N3S
Mol. Mass.:
250.382
SMILES:
CCC[N@H+]1CCC=C2[C@@H]1CCc1sc(N)nc21 |c:6|
Structure:
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