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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50280569
Substrate
n/a
Meas. Tech.
ChEBML_139630
IC50
1630±n/a nM
Citation
 Tecle, H; Mirzadegan, T; Moos, WH; Moreland, DW; Pavia, MR; Schwarz, RD; Davis, RE A rationale for the design and synthesis of m1 selective muscarinic agonists. Bioorg Med Chem Lett 2:821-826 (1992)    Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:
GPCR
Mol. Mass.:
51730.61
Organism:
Homo sapiens (Human)
Description:
P08172
Residue:
466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50280569
Synonyms:
1-Aza-bicyclo[2.2.1]heptan-3-one O-cyclobutyl-oxime | CHEMBL354259
Type:
Small organic molecule
Emp. Form.:
C10H16N2O
Mol. Mass.:
180.2468
SMILES:
C1CC(C1)O\N=C1/CN2CCC1C2 |THB:5:6:12:10.9|
Structure:
Search PDB for entries with ligand similarity: