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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50283719
Substrate
n/a
Meas. Tech.
ChEBML_159463
IC50
1.4±n/a nM
Citation
 Thomas, GJ; Bushnell, DJ; Martin, JA Carbocyclic analogues of hydroxyethylamine containing inhibitors of HIV proteinase Bioorg Med Chem Lett 4:2759-2762 (1994)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50283719
Synonyms:
(S)-N*1*-[(1S,2R)-1-Benzyl-3-((1S,2R)-2-tert-butylcarbamoyl-cyclohexyl)-2-hydroxy-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide | CHEMBL327599
Type:
Small organic molecule
Emp. Form.:
C35H45N5O5
Mol. Mass.:
615.7623
SMILES:
CC(C)(C)NC(=O)[C@@H]1CCCC[C@H]1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1
Structure:
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