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Target
Carbonic anhydrase 2
Ligand
BDBM50288866
Substrate
n/a
Meas. Tech.
ChEBML_45054
Kd
130±n/a nM
Citation
 Sigal, GB; Whitesides, GM Benzenesulfonamide-peptide conjugates as probes for secondary binding sites near the active site of carbonic anhydrase Bioorg Med Chem Lett 6:559-564 (1996)    Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Human
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50288866
Synonyms:
3-Naphthalen-2-yl-2-[2-(4-sulfamoyl-benzoylamino)-acetylamino]-propionic acid | CHEMBL153214
Type:
Small organic molecule
Emp. Form.:
C22H21N3O6S
Mol. Mass.:
455.484
SMILES:
NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(Cc1ccc2ccccc2c1)C(O)=O
Structure:
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