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Target
D(4) dopamine receptor
Ligand
BDBM50290195
Substrate
n/a
Meas. Tech.
ChEBML_58937
IC50
95±n/a nM
Citation
 He, XS; Woodruff, K; Brodbeck, R A new series of selective dopamine D4 ligands: 3-([4-arylpiperazin-1-yl]alkylamino)-2H-1,4-benzoxazines Bioorg Med Chem Lett 7:2399-2402 (1997)    Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50290195
Synonyms:
(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-piperazin-1-yl)-pentyl]-amine; compound with but-2-enedioic acid | CHEMBL80645
Type:
Small organic molecule
Emp. Form.:
C21H28N6O
Mol. Mass.:
380.4866
SMILES:
C(CCNC1=Nc2ccccc2OC1)CCN1CCN(CC1)c1ncccn1 |t:4|
Structure:
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