Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50294115
Substrate
n/a
Meas. Tech.
ChEMBL_570886 (CHEMBL1031083)
Ki
0.35±n/a nM
Citation
 Ehrlich, K; Götz, A; Bollinger, S; Tschammer, N; Bettinetti, L; Härterich, S; Hübner, H; Lanig, H; Gmeiner, P Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding. J Med Chem 52:4923-35 (2009) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50294115
Synonyms:
CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piperazin-1-yl)butyl)H-pyrazolo[1,5-a]pyridine-2-carboxamide
Type:
Small organic molecule
Emp. Form.:
C23H29N5OS
Mol. Mass.:
423.574
SMILES:
CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1
Structure:
Search PDB for entries with ligand similarity: