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Target
Growth factor receptor-bound protein 2
Ligand
BDBM50300043
Substrate
n/a
Meas. Tech.
ChEMBL_593415 (CHEMBL1040543)
IC50
2.65E5±n/a nM
Citation
 Courme, C; Gresh, N; Vidal, M; Lenoir, C; Garbay, C; Florent, JC; Bertounesque, E Synthesis of aryl phosphates based on pyrimidine and triazine scaffolds. Eur J Med Chem 45:244-55 (2010) [PubMed]  Article 
Target
Name:
Growth factor receptor-bound protein 2
Synonyms:
ASH | GRB2 | GRB2 adapter protein | GRB2_HUMAN | Grb2-SH2 | Growth factor receptor-bound protein 2
Type:
Protein
Mol. Mass.:
25205.04
Organism:
Homo sapiens (Human)
Description:
P62993
Residue:
217
Sequence:
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
  
Inhibitor
Name:
BDBM50300043
Synonyms:
CHEMBL573405 | Sodium 2-(4-(2-(4-phosphonatooxyphenoxy)phenyl)-6-(4-phosphonatooxyphenylamino)-1,3,5-triazin-2-ylamino)acetamide
Type:
Small organic molecule
Emp. Form.:
C23H18N6O10P2
Mol. Mass.:
600.3729
SMILES:
NC(=O)CNc1nc(Nc2ccc(OP([O-])([O-])=O)cc2)nc(n1)-c1ccccc1Oc1ccc(OP([O-])([O-])=O)cc1
Structure:
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