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Target
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Ligand
BDBM50305665
Substrate
n/a
Meas. Tech.
ChEMBL_604567 (CHEMBL1065476)
IC50
63000±n/a nM
Citation
 Potter, AJ; Ray, S; Gueritz, L; Nunns, CL; Bryant, CJ; Scrace, SF; Matassova, N; Baker, L; Dokurno, P; Robinson, DA; Surgenor, AE; Davis, B; Murray, JB; Richardson, CM; Moore, JD Structure-guided design of alpha-amino acid-derived Pin1 inhibitors. Bioorg Med Chem Lett 20:586-90 (2010) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:
PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:
PROTEIN
Mol. Mass.:
18248.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502595
Residue:
163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
  
Inhibitor
Name:
BDBM50305665
Synonyms:
5-methyl-1H-benzo[d]imidazole-2-carboxylic acid | CHEMBL596008
Type:
Small organic molecule
Emp. Form.:
C9H8N2O2
Mol. Mass.:
176.172
SMILES:
Cc1ccc2nc([nH]c2c1)C(O)=O
Structure:
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