Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50323754
Substrate
n/a
Meas. Tech.
ChEMBL_646967 (CHEMBL1217108)
Ki
2500±n/a nM
Citation
 Dixon, DD; Sethumadhavan, D; Benneche, T; Banaag, AR; Tius, MA; Thakur, GA; Bowman, A; Wood, JT; Makriyannis, A Heteroadamantyl cannabinoids. J Med Chem 53:5656-66 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50323754
Synonyms:
((6aR,9R,10aR)-1,9-Dihydroxy-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl)-(2-oxa-6-aza-tricyclo[3.3.1.1*3,7*]dec-6-yl)-methanone | CHEMBL1214376
Type:
Small organic molecule
Emp. Form.:
C24H31NO5
Mol. Mass.:
413.5066
SMILES:
CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](O)CC[C@@H]12)C(=O)N1C2CC3CC1CC(C2)O3 |r,TLB:18:20:23.22.24:27.26.28,18:20:27.29.26:24,28:27:20.21.22:24,THB:29:27:20:23.22.24,29:23:20:27.26.28,28:21:27.29.26:24|
Structure:
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