Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50323757
Substrate
n/a
Meas. Tech.
ChEMBL_646967 (CHEMBL1217108)
Ki
7500±n/a nM
Citation
 Dixon, DD; Sethumadhavan, D; Benneche, T; Banaag, AR; Tius, MA; Thakur, GA; Bowman, A; Wood, JT; Makriyannis, A Heteroadamantyl cannabinoids. J Med Chem 53:5656-66 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50323757
Synonyms:
(6aR,9S,10aR)-6,6-Dimethyl-3-(2-oxa-6-aza-tricyclo[3.3.1.1*3,7*]dec-6-ylmethyl)-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromene-1,9-diol | CHEMBL1214435
Type:
Small organic molecule
Emp. Form.:
C24H33NO4
Mol. Mass.:
399.5231
SMILES:
CC1(C)Oc2cc(CN3C4CC5CC3CC(C4)O5)cc(O)c2[C@@H]2C[C@@H](O)CC[C@@H]12 |r,TLB:7:8:11.10.12:15.14.16,12:11:8.13.14:16,THB:7:8:11.17.10:16,17:15:8:11.10.12,17:11:8:15.14.16,12:13:11.17.10:16|
Structure:
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