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Target
Procathepsin L
Ligand
BDBM50325648
Substrate
n/a
Meas. Tech.
ChEMBL_652318 (CHEMBL1225521)
Ki
31700±n/a nM
Citation
 Waag, T; Gelhaus, C; Rath, J; Stich, A; Leippe, M; Schirmeister, T Allicin and derivates are cysteine protease inhibitors with antiparasitic activity. Bioorg Med Chem Lett 20:5541-3 (2010) [PubMed]  Article 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM50325648
Synonyms:
CHEMBL1224167 | S-benzyl phenylmethanesulfinothioate
Type:
Small organic molecule
Emp. Form.:
C14H14OS2
Mol. Mass.:
262.39
SMILES:
O=S(Cc1ccccc1)SCc1ccccc1
Structure:
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