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Target
Myelin-associated glycoprotein
Ligand
BDBM50354047
Substrate
n/a
Meas. Tech.
ChEMBL_770761 (CHEMBL1837431)
Kd
3.2E4±n/a nM
Citation
 Zeng, Y; Rademacher, C; Nycholat, CM; Futakawa, S; Lemme, K; Ernst, B; Paulson, JC High affinity sialoside ligands of myelin associated glycoprotein. Bioorg Med Chem Lett 21:5045-9 (2011) [PubMed]  Article 
Target
Name:
Myelin-associated glycoprotein
Synonyms:
GMA | MAG | MAG_HUMAN
Type:
PROTEIN
Mol. Mass.:
69048.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_770764
Residue:
626
Sequence:
MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK
  
Inhibitor
Name:
BDBM50354047
Synonyms:
CHEMBL1836311
Type:
Small organic molecule
Emp. Form.:
C35H55N2O19Si
Mol. Mass.:
835.8992
SMILES:
CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](OCC[Si](C)(C)C)[C@@H]3O)[C@@H]2O)(O[C@H]1[C@H](O)[C@H](O)CNC(=O)c1ccccc1)C([O-])=O |r|
Structure:
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