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Target
Isocitrate lyase
Ligand
BDBM50358285
Substrate
n/a
Meas. Tech.
ChEMBL_790943 (CHEMBL1925559)
IC50
69900±n/a nM
Citation
 Bouthenet, E; Oh, KB; Park, S; Nagi, NK; Lee, HS; Matthews, SE Synthesis and antimicrobial activity of brominated resorcinol dimers. Bioorg Med Chem Lett 21:7142-5 (2011) [PubMed]  Article 
Target
Name:
Isocitrate lyase
Synonyms:
ACEA_CANAX | ICL1
Type:
PROTEIN
Mol. Mass.:
61398.95
Organism:
Yeast
Description:
ChEMBL_972063
Residue:
550
Sequence:
MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQADKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGITAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIESEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGKDIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKAAVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSNQYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTEDQFKESKAKA
  
Inhibitor
Name:
BDBM50358285
Synonyms:
CHEMBL1922401
Type:
Small organic molecule
Emp. Form.:
C19H14BrNO6
Mol. Mass.:
432.222
SMILES:
Oc1ccc(C(c2cccc(c2)[N+]([O-])=O)c2cc(Br)c(O)cc2O)c(O)c1
Structure:
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