Reaction Details Report a problem with these data
Target
Appetite-regulating hormone
Ligand
BDBM50359232
Substrate
n/a
Meas. Tech.
ChEMBL_790253 (CHEMBL1925646)
Ki
34±n/a nM
Citation
Hoveyda, HR; Marsault, E; Gagnon, R; Mathieu, AP; Vézina, M; Landry, A; Wang, Z; Benakli, K; Beaubien, S; Saint-Louis, C; Brassard, M; Pinault, JF; Ouellet, L; Bhat, S; Ramaseshan, M; Peng, X; Foucher, L; Beauchemin, S; Bhérer, P; Veber, DF; Peterson, ML; Fraser, GL Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic. J Med Chem 54:8305-20 (2011) [PubMed] Article
More Info.:
Target
Name:
Appetite-regulating hormone
Synonyms:
GHRL | GHRL_HUMAN | Ghrelin | Ghrelin-27 | Ghrelin-28 | Growth hormone secretagogue | Growth hormone-releasing peptide | MTLRP | Motilin-related peptide | Obestatin | Protein M46
Type:
PROTEIN
Mol. Mass.:
12908.57
Organism:
Human
Description:
ChEMBL_790253
Residue:
117
Sequence:
MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPEDGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK