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Target
Lipoprotein lipase
Ligand
BDBM50364292
Substrate
n/a
Meas. Tech.
ChEMBL_804419 (CHEMBL1954846)
IC50
15000±n/a nM
Citation
 O'Connell, DP; LeBlanc, DF; Cromley, D; Billheimer, J; Rader, DJ; Bachovchin, WW Design and synthesis of boronic acid inhibitors of endothelial lipase. Bioorg Med Chem Lett 22:1397-401 (2012) [PubMed]  Article 
Target
Name:
Lipoprotein lipase
Synonyms:
LIPD | LIPL_HUMAN | LPL
Type:
PROTEIN
Mol. Mass.:
53173.96
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1280894
Residue:
475
Sequence:
MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG
  
Inhibitor
Name:
BDBM50364292
Synonyms:
CHEMBL1949700
Type:
Small organic molecule
Emp. Form.:
C21H35BO2
Mol. Mass.:
330.312
SMILES:
CCCCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1
Structure:
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