Reaction Details Report a problem with these data
Target
Glycerol kinase
Ligand
BDBM50366481
Substrate
n/a
Meas. Tech.
ChEBML_72907
Ki
2900000±n/a nM
Citation
 Bystrom, CE; Pettigrew, DW; Remington, S; Branchaud, BP ATP analogs with non-transferable groups in the position as inhibitors of glycerol kinase Bioorg Med Chem Lett 7:2613-2616 (1997)    Article 
Target
Name:
Glycerol kinase
Synonyms:
GK | GLPK_HUMAN
Type:
PROTEIN
Mol. Mass.:
61243.96
Organism:
Human
Description:
ChEMBL_72907
Residue:
559
Sequence:
MAASKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKITGEPLYNAVVWLDLRTQSTVESLSKRIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKISHSVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPEDLSAVTMERFEPQINAEESEIRYSTWKKAVMKSMGWVTTQSPESGDPSIFCSLPLGFFIVSSMVMLIGARYISGIP
  
Inhibitor
Name:
BDBM50366481
Synonyms:
CHEMBL606431
Type:
Small organic molecule
Emp. Form.:
C11H18AsN5O12P2
Mol. Mass.:
549.156
SMILES:
Nc1ncnc2n(cnc12)C1O[C@H](COP(O)(=O)OP(O)(=O)C[As](O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: