Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50242856
Substrate
n/a
Meas. Tech.
ChEBML_58464
Ki
3900±n/a nM
Citation
 Hegde, VR; Dai, P; Ladislaw, C; Patel, MG; Puar, MS; Pachter, JA D4 dopamine receptor-selective compounds from the Chinese plant Phoebe chekiangensis Bioorg Med Chem Lett 7:1207-1212 (1997)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50242856
Synonyms:
(1R)-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol | (R)-norcoclaurine | CHEMBL501778
Type:
Small organic molecule
Emp. Form.:
C16H17NO3
Mol. Mass.:
271.3111
SMILES:
Oc1ccc(C[C@H]2NCCc3cc(O)c(O)cc23)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: