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Target
D(3) dopamine receptor
Ligand
BDBM50091902
Substrate
n/a
Meas. Tech.
ChEBML_62278
Ki
580±n/a nM
Citation
 Einsiedel, J; Thomas, C; Hübner, H; Gmeiner, P Phenyloxazoles and phenylthiazoles as benzamide bioisosteres: synthesis and dopamine receptor binding profiles. Bioorg Med Chem Lett 10:2041-4 (2001) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50091902
Synonyms:
(1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine | CHEMBL293225
Type:
Small organic molecule
Emp. Form.:
C23H26BrN3O2
Mol. Mass.:
456.375
SMILES:
COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)co1
Structure:
Search PDB for entries with ligand similarity: