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Target
D(4) dopamine receptor
Ligand
BDBM50109941
Substrate
n/a
Meas. Tech.
ChEBML_60674
Ki
2.7±n/a nM
Citation
 Löber, S; Aboul-Fadl, T; Hübner, H; Gmeiner, P Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. Bioorg Med Chem Lett 12:633-6 (2002) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50109941
Synonyms:
3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-methylH-pyrazolo[1,5-a]pyridine | 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-methyl-pyrazolo[1,5-a]pyridine | 4-(4-Chloro-phenyl)-1-(7-methyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium | CHEMBL423247
Type:
Small organic molecule
Emp. Form.:
C19H21ClN4
Mol. Mass.:
340.85
SMILES:
Cc1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12
Structure:
Search PDB for entries with ligand similarity: