Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50273466
Substrate
n/a
Meas. Tech.
ChEBML_226561
IC50
438±n/a nM
Citation
 Wikström, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B N-substituted 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines and 3-phenylpiperidines: effects on central dopamine and sigma receptors. J Med Chem 30:2169-74 (1988) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50273466
Synonyms:
(+/-)-trans-4-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-7-ol | 4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol | CHEMBL450863
Type:
Small organic molecule
Emp. Form.:
C16H23NO
Mol. Mass.:
245.3599
SMILES:
CCCN1CCC[C@@H]2[C@@H]1CCc1c(O)cccc21 |r|
Structure:
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