Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50006080
Substrate
n/a
Meas. Tech.
ChEBML_221704
IC50
1520±n/a nM
Citation
 Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem 35:1650-62 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Guinea pig
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50006080
Synonyms:
3-{3-[(2-Acetyl-5-tetradecyloxy-phenoxy)-hydroxy-phosphoryloxy]-benzyl}-5-methyl-thiazol-3-ium | CHEMBL43887
Type:
Small organic molecule
Emp. Form.:
C33H46NO6PS
Mol. Mass.:
615.76
SMILES:
CCCCCCCCCCCCCCOc1ccc(C(C)=O)c(OP([O-])(=O)Oc2cccc(C[n+]3csc(C)c3)c2)c1
Structure:
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