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Target
D(1A) dopamine receptor
Ligand
BDBM50067809
Substrate
n/a
Meas. Tech.
ChEMBL_58348 (CHEMBL884447)
IC50
20000±n/a nM
Citation
 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q Modified ibogaine fragments: synthesis and preliminary pharmacological characterization of 3-ethyl-5-phenyl-1,2,3,4,5, 6-hexahydroazepino[4,5-b]benzothiophenes. J Med Chem 41:4486-91 (1998) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50067809
Synonyms:
3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indole | CHEMBL23529
Type:
Small organic molecule
Emp. Form.:
C19H20N2
Mol. Mass.:
276.3755
SMILES:
CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1
Structure:
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