Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50076466
Substrate
n/a
Meas. Tech.
ChEMBL_147722 (CHEMBL759192)
IC50
158±n/a nM
Citation
 Nandanan, E; Camaioni, E; Jang, SY; Kim, YC; Cristalli, G; Herdewijn, P; Secrist, JA; Tiwari, KN; Mohanram, A; Harden, TK; Boyer, JL; Jacobson, KA Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists. J Med Chem 42:1625-38 (1999) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50076466
Synonyms:
2-(6-Methylamino-purin-9-yl)-5,7,9,11-tetraoxo-tetrahydro-1,4,6,8,10,12-hexaoxa-5lambda*5*,7lambda*5*,9lambda*5*,11lambda*5*-tetraphospha-cyclopentacyclododecene-5,7,9,11-tetraol | CHEMBL296960
Type:
Small organic molecule
Emp. Form.:
C11H17N5O14P4
Mol. Mass.:
567.1728
SMILES:
CNc1ncnc2n(cnc12)C1CC2OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OCC2O1
Structure:
Search PDB for entries with ligand similarity: