Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50369519
Substrate
n/a
Meas. Tech.
ChEMBL_145280 (CHEMBL751216)
Ki
0.380000±n/a nM
Citation
 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. J Med Chem 43:114-22 (2000) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
Guinea pig
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50369519
Synonyms:
CHEMBL1202427
Type:
Small organic molecule
Emp. Form.:
C21H27NO3
Mol. Mass.:
341.444
SMILES:
Oc1ccc2C(=O)C3C4CCCCC4(CCN3CC3CCCO3)c2c1 |TLB:6:5:8:14.15.16,24:23:8:14.15.16,THB:17:16:8:4.5.23,9:8:14.15.16:4.5.23|
Structure:
Search PDB for entries with ligand similarity: