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Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50092566
Substrate
n/a
Meas. Tech.
ChEMBL_48591 (CHEMBL662471)
IC50
>10000±n/a nM
Citation
 Martín-Martínez, M; De La Figuera, N; Latorre, M; Herranz, R; García-López, MT; Cenarruzabeitia, E; Del Río, J; González-Muñiz, R beta-Turned dipeptoids as potent and selective CCK(1) receptor antagonists. J Med Chem 43:3770-7 (2000) [PubMed]  Article 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
Cckbr | Cholecystokinin A | Cholecystokinin B receptor | Cholecystokinin receptor | GASR_RAT | Gastrin/cholecystokinin type B receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48980.43
Organism:
RAT
Description:
Cholecystokinin A CCKBR RAT::P30553
Residue:
452
Sequence:
MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTMVQPVGPRVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGLISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCVQLPRSRLEMTTLTTPTPGPVPGPRPNQAKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTWRAFDGPGAQRALSGAPISFIHLLSYVSACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPQPLPDEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50092566
Synonyms:
(2S,5S,11bR,1'S)-[5-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indol-2-yl]-carbamic acid benzyl ester | CHEMBL337988
Type:
Small organic molecule
Emp. Form.:
C32H31N5O5
Mol. Mass.:
565.619
SMILES:
NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H]2C[C@H](NC(=O)OCc3ccccc3)C(=O)N12
Structure:
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