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Target
D(3) dopamine receptor
Ligand
BDBM50167896
Substrate
n/a
Meas. Tech.
ChEMBL_303138 (CHEMBL829066)
Ki
3.98±n/a nM
Citation
 Newman, AH; Grundt, P; Nader, MA Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. J Med Chem 48:3663-79 (2005) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50167896
Synonyms:
CHEMBL195762 | N-{4-[2-(7-Methanesulfonyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethyl]-cyclohexyl}-3-(5-methyl-[1,2,4]oxadiazol-3-yl)-benzamide
Type:
Small organic molecule
Emp. Form.:
C29H36N4O4S
Mol. Mass.:
536.686
SMILES:
Cc1nc(no1)-c1cccc(c1)C(=O)NC1CC[C@H](CCN2CCc3ccc(cc3CC2)S(C)(=O)=O)CC1 |wD:18.20,(-7.59,-1.32,;-6.06,-1.15,;-5.02,-2.3,;-3.62,-1.68,;-3.78,-.15,;-5.28,.18,;-2.28,-2.46,;-2.28,-4.01,;-.95,-4.78,;.38,-4.01,;.38,-2.46,;-.95,-1.68,;1.71,-1.67,;1.71,-.12,;3.06,-2.44,;4.4,-1.67,;4.38,-.12,;5.73,.65,;7.07,-.12,;8.4,.65,;9.73,-.12,;11.07,.65,;10.97,2.17,;12.1,3.23,;13.62,3.01,;14.39,4.34,;15.92,4.34,;16.7,3.01,;15.93,1.68,;14.39,1.68,;13.84,.23,;12.35,-.23,;18.25,3.01,;19.79,3.01,;18.24,4.55,;18.25,1.47,;7.07,-1.67,;5.74,-2.44,)|
Structure:
Search PDB for entries with ligand similarity: