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Target
D(3) dopamine receptor
Ligand
BDBM50129428
Substrate
n/a
Meas. Tech.
ChEMBL_302429 (CHEMBL829665)
Ki
1.4±n/a nM
Citation
 Newman, AH; Grundt, P; Nader, MA Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. J Med Chem 48:3663-79 (2005) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50129428
Synonyms:
CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-4-iodo-benzamide | Quinoxaline-1-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Type:
Small organic molecule
Emp. Form.:
C21H24Cl2IN3O
Mol. Mass.:
532.245
SMILES:
Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)cc3)CC2)c1Cl
Structure:
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