Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50372285
Substrate
n/a
Meas. Tech.
ChEMBL_464846 (CHEMBL930563)
Ki
25500±n/a nM
Citation
 González, MP; Besada, P; González Moa, MJ; Teijeira, M; Terán, C New QSAR combined strategy for the design of A1 adenosine receptor agonists. Bioorg Med Chem 16:1658-75 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50372285
Synonyms:
CHEMBL257684
Type:
Small organic molecule
Emp. Form.:
C18H18IN5O
Mol. Mass.:
447.2729
SMILES:
OCC1CC=CC1n1cnc2c(NCc3ccccc3I)ncnc12 |w:2.1,6.7,c:4|
Structure:
Search PDB for entries with ligand similarity: