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Target
Cyclin-dependent kinase 1
Ligand
BDBM50267719
Substrate
n/a
Meas. Tech.
ChEMBL_563812 (CHEMBL994324)
IC50
>500000±n/a nM
Citation
 Gray, NS; Wodicka, L; Thunnissen, AM; Norman, TC; Kwon, S; Espinoza, FH; Morgan, DO; Barnes, G; LeClerc, S; Meijer, L; Kim, SH; Lockhart, DJ; Schultz, PG Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281:533-538 (1998) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC28 | CDK1 | CDK1_YEAST | Cell division control protein 28 | HSL5 | SRM5
Type:
PROTEIN
Mol. Mass.:
34067.63
Organism:
Baker's yeast
Description:
ChEMBL_563811
Residue:
298
Sequence:
MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES
  
Inhibitor
Name:
BDBM50267719
Synonyms:
2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9H-purin-2-ylamino)ethanol | CHEMBL519036
Type:
Small organic molecule
Emp. Form.:
C17H21ClN6O
Mol. Mass.:
360.841
SMILES:
CC(C)n1cnc2c(nc(NCCO)nc12)N(C)c1cccc(Cl)c1
Structure:
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