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Target
P2Y purinoceptor 1
Ligand
BDBM50268012
Substrate
n/a
Meas. Tech.
ChEMBL_521734 (CHEMBL1005024)
EC50
80±n/a nM
Citation
 Eliahu, SE; Camden, J; Lecka, J; Weisman, GA; Sévigny, J; Gélinas, S; Fischer, B Identification of hydrolytically stable and selective P2Y(1) receptor agonists. Eur J Med Chem 44:1525-36 (2009) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50268012
Synonyms:
{[({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphinato]methyl}phosphonate
Type:
Small organic molecule
Emp. Form.:
C12H16N5O12P3S
Mol. Mass.:
547.27
SMILES:
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)CP([O-])([O-])=O)[C@@H](O)[C@H]3O)c2n1 |r|
Structure:
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