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Target
P2Y purinoceptor 1
Ligand
BDBM50267999
Substrate
n/a
Meas. Tech.
ChEMBL_521715 (CHEMBL1001626)
EC50
28±n/a nM
Citation
 Eliahu, SE; Camden, J; Lecka, J; Weisman, GA; Sévigny, J; Gélinas, S; Fischer, B Identification of hydrolytically stable and selective P2Y(1) receptor agonists. Eur J Med Chem 44:1525-36 (2009) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1_RAT | P2Y1 | P2ry1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
PROTEIN
Mol. Mass.:
42338.46
Organism:
Rattus norvegicus
Description:
ChEMBL_873671
Residue:
373
Sequence:
MTEVPWSAVPNGTDAAFLAGLGSLWGNSTIASTAAVSSSFRCALIKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGIRKNKTVTCYDSTSDEYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL
  
Inhibitor
Name:
BDBM50267999
Synonyms:
({[({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy}(boranuidyl)phosphoryl)oxy]phosphinato}oxy)phosphonate | CHEMBL601711
Type:
Small organic molecule
Emp. Form.:
C11H17BN5O12P3S
Mol. Mass.:
547.078
SMILES:
[BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(SC)nc12)OP([O-])(=O)OP([O-])([O-])=O |r|
Structure:
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