Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50309030
Substrate
n/a
Meas. Tech.
ChEMBL_612941 (CHEMBL1070893)
Ki
1578±n/a nM
Citation
 Scott, JD; Li, SW; Wang, H; Xia, Y; Jayne, CL; Miller, MW; Duffy, RA; Boykow, GC; Kowalski, TJ; Spar, BD; Stamford, AW; Chackalamannil, S; Lachowicz, JE; Greenlee, WJ Diaryl piperidines as CB1 receptor antagonists. Bioorg Med Chem Lett 20:1278-83 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50309030
Synonyms:
(3R,6S)-1-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-N-isobutylpiperidine-3-sulfonamide | CHEMBL600064
Type:
Small organic molecule
Emp. Form.:
C21H25Cl3N2O2S
Mol. Mass.:
475.859
SMILES:
CC(C)CNS(=O)(=O)[C@@H]1CC[C@H](N(C1)c1ccc(Cl)cc1)c1ccc(Cl)cc1Cl |r|
Structure:
Search PDB for entries with ligand similarity: