Reaction Details Report a problem with these data
Target
Succinyl-diaminopimelate desuccinylase
Ligand
BDBM50067893
Substrate
n/a
Meas. Tech.
ChEMBL_617887 (CHEMBL1101552)
IC50
>10000000±n/a nM
Citation
 Gillner, D; Armoush, N; Holz, RC; Becker, DP Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. Bioorg Med Chem Lett 19:6350-2 (2009) [PubMed]  Article 
Target
Name:
Succinyl-diaminopimelate desuccinylase
Synonyms:
DAPE_HAEIN | dapE
Type:
PROTEIN
Mol. Mass.:
41343.05
Organism:
Haemophilus influenzae
Description:
ChEMBL_617887
Residue:
377
Sequence:
MKEKVVSLAQDLIRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEPVIAFAGHTDVVPTGDENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANPNHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRGSITGNLYIQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAGTGSNNVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGKLLDSITSAIEETIGITPKAETGGGTSDGRFIALMGAEVVEFGPLNSTIHKVNECVSVEDLGKCGEIYHKMLVNLLDS
  
Inhibitor
Name:
BDBM50067893
Synonyms:
3-Carboxyphenylboronicacid | 3-boronobenzoic acid | 3-phenyl ester boronic acid | CHEMBL421765
Type:
Small organic molecule
Emp. Form.:
C7H7BO4
Mol. Mass.:
165.939
SMILES:
OB(O)c1cccc(c1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: