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Target
Sialidase-2
Ligand
BDBM50314987
Substrate
n/a
Meas. Tech.
ChEMBL_623928 (CHEMBL1108053)
Ki
740000±n/a nM
Citation
 Chavas, LM; Kato, R; Suzuki, N; von Itzstein, M; Mann, MC; Thomson, RJ; Dyason, JC; McKimm-Breschkin, J; Fusi, P; Tringali, C; Venerando, B; Tettamanti, G; Monti, E; Wakatsuki, S Complexity in influenza virus targeted drug design: interaction with human sialidases. J Med Chem 53:2998-3002 (2010) [PubMed]  Article 
Target
Name:
Sialidase-2
Synonyms:
Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2
Type:
PROTEIN
Mol. Mass.:
42256.20
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960638
Residue:
380
Sequence:
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYLPQ
  
Inhibitor
Name:
BDBM50314987
Synonyms:
(2S,3R,4R)-3-acetamido-4-hydroxy-2-(3-hydroxypropoxy)-3,4-dihydro-2H-pyran-6-carboxylic acid | CHEMBL1090838
Type:
Small organic molecule
Emp. Form.:
C11H17NO7
Mol. Mass.:
275.2552
SMILES:
CC(=O)N[C@@H]1[C@H](O)C=C(O[C@@H]1OCCCO)C(O)=O |r,c:7|
Structure:
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